drugset / Trial / NCT03653520

Conscious Sedation Efficacy of the MKO Melt (Midazolam, Ketamine, Ondansetron)

NCT03653520

Completed 651 enrolled Avanti Anesthesia
RandomizedParallel-groupSingle-blindTreatment

Summary

The investigators hypothesized that the combination of Valium, Tramadol and Zofran is superior to the substantially more expensive MKO melt in patient satisfaction after cataract surgery.

Timeline

Start
2017-06-28
Primary completion
2017-11-02
Completion
2017-11-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Diazepam Small molecule 5 mg Oral
Comparator Diazepam Small molecule 10 mg Oral
Subject Ketamine Small molecule 25 mg Subcutaneous
Subject Ketamine Small molecule 50 mg Subcutaneous
Subject Midazolam Small molecule 3 mg Subcutaneous
Subject Midazolam Small molecule 6 mg Subcutaneous
Comparator Ondansetron Other / unclassified 2 mg Oral
Comparator Ondansetron Other / unclassified 4 mg Oral
Comparator Tramadol Other / unclassified 50 mg Oral
Comparator Tramadol Other / unclassified 100 mg Oral

Indications