drugset / Trial / NCT03672669

Comparison of the Effect of A-PRF and L-PRF on Outcomes After Removal of Impacted Mandibular Third Molar

NCT03672669

Completed 27 enrolled Near East University, Turkey
RandomizedCrossoverDouble-blindSupportive care

Summary

In this study, it was aimed to investigating and comparing the postoperative effects of leukocyte- and platelet-rich fibrin (L-PRF) and advanced platelet-rich fibrin (A-PRF) in terms of pain, swelling on the cheek, and trismus after mandibular third molar surgery. The study included a total of 27 patients with bilateral impacted mandibular third molar which surgically operated at different times. Patients were evaluated in two randomly separated groups. For the first group; A-PRF and for the second group; L-PRF was applied into the tooth socket. The outcomes variables were; pain, swelling, the number of analgesics taken, and trismus. These variables were also assessed on the basis of; 1st, 2nd, 3rd and 7th days following the operation.

Timeline

Start
2017-11-05
Primary completion
2018-03-01
Completion
2018-05-20

Drugs

EvaluationDrugModalityDoseRoute
Comparator Advanced Platelet Rich Fibrin Other / unclassified Other
Comparator Platelet Concentrate Other / unclassified Other

Indications

No indication recorded.