Platelet rich fibrin
Trials 45
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 02 trials | ||||||
| Phase 0 | NCT04495205 | Jan 2020 → Mar 2021 | gingival disorder | Cairo University | Unknown | No outcome recorded |
| Phase 0 | NCT03313934 | Nov 2017 → Nov 2018 | — | Rejuva Medical Aesthetics | Unknown | No outcome recorded |
| Phase 11 trial | ||||||
| Phase 1 | NCT03878771 | Mar → Apr 2019 | Stevens-Johnson syndrome, mucous membrane pemphigoid, pemphigus vulgaris | Beni-Suef University | Completed | No outcome recorded |
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT06634017 | Apr 2024 → Apr 2025 overdue | — | Dow University of Health Sciences | Recruiting | No outcome recorded |
| Phase 25 trials | ||||||
| Phase 2 | NCT07798258 | Oct 2025 → Jan 2027 expected | temporomandibular joint disorder | Cairo University | Active not recruiting | No outcome recorded |
| Phase 2 | NCT07293962 | Apr 2024 → Mar 2026 overdue | periodontitis, chronic, adult | Mahsa University | Recruiting | No outcome recorded |
| Phase 2 | NCT07359924 | Feb → Aug 2022 | skin atrophy | Poznan University of Medical Sciences | Completed | No outcome recorded |
| Phase 2 | NCT05593731 | Dec 2021 → Jul 2022 | — | Misr University for Science and Technology | Completed | No outcome recorded |
| Phase 2 | NCT01612845 | May 2007 → May 2009 | rotator cuff syndrome | Hospital Universitario La Paz | Completed | No outcome recorded |
| Phase 2/32 trials · 1 met primary | ||||||
| Phase 2/3 | NCT05264467 | Mar 2018 → Jul 2021 | intestinal perforation | Universidad de Concepcion | Completed | No outcome recorded |
| Phase 2/3 | NCT00931567 | Aug 2007 → Feb 2010 | palmar fibromatosis | Centre Hospitalier Universitaire de Nice | Completed | Met primary |
| Phase 33 trials | ||||||
| Phase 3 | NCT05196503 | Feb 2022 overdue | chronic pain syndrome, neuropathy, painful | University Hospital, Strasbourg, France | Recruiting | No outcome recorded |
| Phase 3 | NCT04864197 | Dec 2019 → Jul 2020 | gingival hypertrophy | University of Baghdad | Unknown | No outcome recorded |
| Phase 3 | NCT02982681 | Apr 2015 → Aug 2016 | bone resorption disease, chronic periodontitis | Dr. D. Y. Patil Dental College & Hospital | Completed | No outcome recorded |
| Phase 44 trials | ||||||
| Phase 4 | NCT06776289 | Mar → Jul 2026 overdue | periapical periodontitis | Mark Schachman | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06905860 | Jun 2025 → Jun 2027 expected | osteoarthritis, knee | Federal University of São Paulo | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT04839276 | Jan → Jun 2018 | laryngeal adductor paralysis | Faculty of Medicine, University of Indonesia | Completed | No outcome recorded |
| Phase 4 | NCT05904158 | Jun 2010 → Aug 2022 | — | Hacettepe University | Completed | No outcome recorded |
| Phase not applicable27 trials · 1 missed | ||||||
| — | NCT07595198 | Jun 2026 → Jun 2027 expected | — | Ohio State University | Not yet recruiting | No outcome recorded |
| — | NCT07790653 | Feb → Sep 2026 overdue | alveolar periostitis | CMH Lahore Medical College and Institute of Dentistry | Active not recruiting | No outcome recorded |
| — | NCT07672951 | Dec 2025 → May 2026 | impacted teeth, multiple | PAEC General Hospital, Islamabad | Completed | No outcome recorded |
| — | NCT07424716 | May 2025 → Apr 2026 overdue | odontogenic cyst | Sana'a University | Recruiting | No outcome recorded |
| — | NCT06573502 | Mar → Sep 2025 | osteoarthritis | Aliaa Babekir Ahmed Mohamed | Completed | No outcome recorded |
| — | NCT07530068 | Feb → Nov 2025 | impacted teeth, multiple | Gazi University | Completed | No outcome recorded |
| — | NCT07033351 | Feb → Jun 2025 | — | Al-Mustansiriyah University | Completed | No outcome recorded |
| — | NCT07242729 | Feb 2025 → Feb 2027 expected | plantar fasciitis | Federal University of São Paulo | Recruiting | No outcome recorded |
| — | NCT07408895 | May → Sep 2024 | — | Sana'a University | Completed | No outcome recorded |
| — | NCT07600619 | May → Nov 2024 | impacted teeth, multiple | Hasanuddin University | Completed | No outcome recorded |
| — | NCT06037070 | May 2024 → May 2025 | — | Al-Mustansiriyah University | Unknown | No outcome recorded |
| — | NCT07525531 | Apr 2024 → Aug 2025 | periodontitis | Ondokuz Mayıs University | Completed | No outcome recorded |
| — | NCT07561671 | Feb 2024 → Sep 2025 | dermis disorder | Zagazig University | Completed | No outcome recorded |
| — | NCT06900894 | Oct 2023 → Jan 2024 | impacted teeth, multiple | Mustafa Kemal University | Completed | No outcome recorded |
| — | NCT06165692 | Oct 2022 → Oct 2023 | impacted teeth, multiple, malposition of teeth with or without hypodontia/oligodontia | Amerigo Giudice | Completed | No outcome recorded |
| — | NCT05517187 | Mar 2022 → Mar 2023 | dental pulp necrosis | Nahda University | Unknown | No outcome recorded |
| — | NCT05215197 | Jan 2022 → Dec 2028 expected | sensorineural hearing loss disorder | Pamukkale University | Recruiting | No outcome recorded |
| — | NCT07841301 | Dec 2021 → May 2023 | periodontal disorder | Medical University of Sofia | Completed | No outcome recorded |
| — | NCT06358352 | Oct 2021 → Feb 2022 | bone development disease | Mansoura University | Completed | No outcome recorded |
| — | NCT05517733 | Jun 2021 → Jun 2022 | — | Nourhan M.Aly | Completed | No outcome recorded |
| — | NCT05161455 | Jun 2021 → Mar 2023 | — | King Saud University | Completed | No outcome recorded |
| — | NCT04070729 | Aug → Nov 2019 | chronic periodontitis | Institute of Dental Sciences, Bareilly, Uttar Pradesh, India | Unknown | No outcome recorded |
| — | NCT03814707 | Jan → Jun 2019 | — | mostafa soliman | Unknown | No outcome recorded |
| — | NCT03685396 | Nov 2017 → Jul 2018 | gingival recession | Azienda Ospedaliera San Paolo | Completed | No outcome recorded |
| — | NCT07604584 | May 2017 → Dec 2018 | impacted teeth, multiple | Ankara University | Completed | No outcome recorded |
| — | NCT02652169 | Jun 2014 → Dec 2025 overdue | chronic ulcer of skin | Medical University of Vienna | Recruiting | No outcome recorded |
| — | NCT02397122 | Feb → Dec 2013 | gingival recession | Kırıkkale University | Completed | Missed primary |
| Comparator or background therapy28 trials | ||||||
| Phase 0 | NCT02810548 Comparator | Feb 2015 → Nov 2016 | disease of bone structure | King Abdulaziz University | Completed | No outcome recorded |
| Phase 1 | NCT07090694 Comparator | Feb → Aug 2025 overdue | external pathological resorption | Dar Al Uloom University | Enrolling by invitation | No outcome recorded |
| Phase 1/2 | NCT07508033 Comparator | Jan → Jul 2026 overdue | periodontal disorder | Al Salam University | Recruiting | No outcome recorded |
| Phase 2 | NCT03707483 Background | Feb → Nov 2019 | periodontal disorder | Cairo University | Unknown | No outcome recorded |
| Phase 2 | NCT02120872 Comparator | Feb 2013 → Jan 2014 | chronic periodontitis | Government Dental College and Research Institute, Bangalore | Completed | No outcome recorded |
| Phase 2 | NCT02119520 Comparator | Feb 2013 → Feb 2014 | chronic periodontitis | Government Dental College and Research Institute, Bangalore | Completed | No outcome recorded |
| Phase 2/3 | NCT02836678 Comparator | Jan 2017 → Sep 2018 | mouth disorder | Cairo University | Unknown | No outcome recorded |
| Phase 2/3 | NCT02516111 Comparator | Sep 2014 → May 2015 | chronic periodontitis | Government Dental College and Research Institute, Bangalore | Completed | No outcome recorded |
| Phase 3 | NCT06662604 Comparator | Oct 2024 → Sep 2025 overdue | cysts and fistulae of the face and oral cavity | Cairo University | Not yet recruiting | No outcome recorded |
| Phase 3 | NCT07366762 Comparator | Jul 2024 → May 2025 | female stress incontinence | Kafrelsheikh University | Completed | No outcome recorded |
| Phase 4 | NCT07437209 Comparator | Dec 2024 → Dec 2025 | periodontitis, aggressive | Center for Advanced Rejuvenation and Esthetics | Completed | No outcome recorded |
| Phase 4 | NCT04757740 Comparator | Mar 2021 → Sep 2022 | — | Fayoum University Hospital | Completed | No outcome recorded |
| Phase 4 | NCT04773886 Comparator | Feb 2020 → Mar 2021 | pulpitis | Maharishi Markendeswar University (Deemed to be University) | Completed | No outcome recorded |
| Phase 4 | NCT04377698 Comparator | Jan 2018 → Nov 2019 | periapical periodontitis | Saraswati Dental College | Completed | No outcome recorded |
| Phase 4 | NCT04131894 Comparator | Dec 2016 → Apr 2018 | disease of bone structure | Bahçeşehir University | Completed | No outcome recorded |
| Phase 4 | NCT02369250 Comparator | Nov 2013 → Jul 2014 | — | Government Dental College and Research Institute, Bangalore | Completed | No outcome recorded |
| — | NCT07543926 Comparator | Apr → Nov 2026 expected | common wart | Sohag University | Not yet recruiting | No outcome recorded |
| — | NCT07239193 Background | Dec 2025 → Jul 2026 overdue | — | Cairo University | Not yet recruiting | No outcome recorded |
| — | NCT07292870 Comparator | Aug 2025 → Dec 2027 expected | periodontitis, aggressive | Universitaire Ziekenhuizen KU Leuven | Recruiting | No outcome recorded |
| — | NCT07013682 Comparator | May 2025 → Dec 2027 expected | periodontitis | University of Bern | Recruiting | No outcome recorded |
| — | NCT06782035 Comparator | Jan → Mar 2025 overdue | gingival recession | Izmir Katip Celebi University | Recruiting | No outcome recorded |
| — | NCT06207955 Comparator | Jan 2024 → Apr 2025 | temporomandibular joint disorder | Fayoum University | Completed | No outcome recorded |
| — | NCT06764732 Background | Nov 2022 → Nov 2023 | — | Al-Azhar University | Completed | No outcome recorded |
| — | NCT05285293 Background | Jun → Dec 2022 | periodontal disorder | Cairo University | Unknown | No outcome recorded |
| — | NCT03672669 Comparator | Nov 2017 → Mar 2018 | — | Near East University, Turkey | Completed | No outcome recorded |
| — | NCT03159338 Comparator | Sep 2017 → May 2018 | — | Shiraz University of Medical Sciences | Unknown | No outcome recorded |
| — | NCT03049137 Background | Feb → Sep 2017 | bone resorption disease | Cairo University | Unknown | No outcome recorded |
| — | NCT03851289 Background | Apr 2016 → Jul 2017 | — | University of Malaya | Completed | No outcome recorded |
Evidence & citations 14 cited values
Every value below carries the sentence it was read from. 76 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Platelet Rich Fibrin | “The objective of this study was to prospectively evaluate the influence of local application of Platelet Rich Fibrin (PRF) on the functional outcome and integrity of the...” NCT01612845 ↗70“PRF platelet rich fibrin. (second-generation Platelet rich plasma where autologous platelets and leucocytes are present in a complex fibrin matrix to accelerate the healing of...” NCT02836678 ↗ “Participants in the I-PRF group will receive 1.5 cc of injectable platelet-rich fibrin (I-PRF) injected into the retrocondylar tissues of the temporomandibular joint at 0, 2,...” NCT07798258 ↗ “Slow release of growth factors and thrombospondin-1 in Choukroun's platelet-rich fibrin (PRF): a gold standard to achieve for all surgical platelet concentrates technologies.” PMID 19089687 ↗ Feb 2009 “Platelet-rich fibrin (PRF) and locally administered antibiotics, including minocycline, have individually shown clinical advantages” NCT07437209 ↗ “Application of autologous platelets gel (Platelet Rich Fibrin) after the " open palm " surgical treatment of Dupuytren's disease.” NCT00931567 ↗ “Platelet-rich fibrin (PRF) acts as a scaffold that inhibits the early migration of epithelial cells into the periodontal tissues.” NCT07013682 ↗ “Platelet Rich Fibrin (PRF) is a form of concentrated suspension of growth factors that promote healing and tissue regeneration.” NCT04495205 ↗ “Platelet-Rich Fibrin (PRF) membranes influence the repair of both gingival and osseous tissues adjacent to dental implants.” NCT07033351 ↗ “Efficacy of Platelet Rich Fibrin in the Prevention of Residual Neuropathic Pain Following Disc Herniation Surgery” NCT05196503 ↗ “Platelet Rich Plasma Combined With Platelet Rich Fibrin in Management of Temporomandibular Joint Osteoarthritis” NCT06573502 ↗ |
| Known as | Autologous Platelet-Rich Fibrin (PRF) | “Autologous Platelet-Rich Fibrin (PRF)” NCT07508033 ↗ |
| Known as | Autologous platelets gel | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00931567 ↗ |
| Known as | I-PRF | “Participants in the I-PRF group will receive 1.5 cc of injectable platelet-rich fibrin (I-PRF) injected into the retrocondylar tissues of the temporomandibular joint at 0, 2,...” NCT07798258 ↗2“compare the therapeutic effect of periurethral injection of autologous platelet-rich plasma (PRP) and injectable platelet rich fibrin (i-PRF)” NCT07366762 ↗ “injection of liquid platelet rich fibrin (I-PRF )” NCT06207955 ↗ |
| Known as | L-PRF | “Leukocyte and and platelet-rich fibrin plasma (L-PRF) is second generation platelet concentrate” NCT05264467 ↗ |
| Known as | Leukocyte and and Platelet-rich Fibrin Plasma | “Leukocyte and and platelet-rich fibrin plasma (L-PRF) is second generation platelet concentrate” NCT05264467 ↗ |
| Known as | leukocyte and platelet rich fibrin | “use of the blood derivative L-PRF (leukocyte and platelet rich fibrin)” NCT07292870 ↗ |
| Known as | leukocyte and platelet-rich fibrin plasma | “leukocyte and platelet-rich fibrin plasma (L-PRF) has been proposed to stimulate and improve cicatrization in colorectal anastomosis” NCT05264467 ↗ |
| Known as | Platelet-Rich Fibrin (PRF) | “It has been reported that the use of Platelet-Rich Fibrin (PRF) to cover palatal wounds accelerates healing and reduces postoperative morbidity.” NCT06782035 ↗1“Autologous Platelet-Rich Fibrin (PRF)” NCT07508033 ↗ |
| Known as | PRF | “Platelet-rich fibrin (PRF) was prepared from autologous venous blood by centrifugation at 2700 rpm for 12 minutes, processed into a membrane, adapted to the size of the...” NCT07525531 ↗39“The purpose of the present study was to investigate the efficacy of autologous Platelet rich fibrin (PRF) or PRF and Simvastatin (SMV) with open flap debridement (OFD) in the...” NCT02120872 ↗ “The Effect of Combination of Vitamin C and Platelet Rich Fibrin (PRF) Versus Platelet Rich Fibrin Alone on Clinical Attachment Gain in Patients With Stage III Periodontitis: A...” NCT03707483 ↗ “Platelet-rich fibrin (PRF) is a preparation made from the patient's own blood that contains platelets, white blood cells, fibrin, and growth factors that may promote tissue...” NCT07790653 ↗ “The goal of this randomized controlled trial is to compare the response of different bone densities to treatment with Platelet Rich Fibrin (PRF) in patients who need treatment...” NCT06037070 ↗ “The study was conducted yo investigate the effects of platelet-rich fibrin (PRF) on the knee stability and function in patients with anterior cruciate ligament (ACL) reconstruction.” NCT05904158 ↗ “Combining Restylane-L with Platelet Rich Fibrin (PRF) will be studied to evaluate if PRF enhances the volumization and skin quality of the treated areas.” NCT03313934 ↗ “This intervention utilizes autologous platelet-rich fibrin (PRF) as the sole grafting material during transcrestal sinus floor elevation.” NCT07090694 ↗ “Extraction sockets were filled with mixture of undemineralized autogenous dentin graft and platelet rich fibrin (PRF) (21 sockets).” NCT04131894 ↗ “Platelet-rich fibrin (PRF) acts as a scaffold that inhibits the early migration of epithelial cells into the periodontal tissues.” NCT07013682 ↗ “Platelet Rich Fibrin (PRF) is a form of concentrated suspension of growth factors that promote healing and tissue regeneration.” NCT04495205 ↗ |
| Known as | S-PRF | “Liquid S-PRF irrigation after root debridement” NCT07293962 ↗ |
| Known as | vivostat | “In 14 patients, after the repair was completed, 6 cc. of PRF (vivostat ®) were locally applied to the repair site.” NCT01612845 ↗ |
| Modality | Other / unclassified | “PRF is a 2nd generation platelet concentrate” NCT04864197 ↗ |
| Route | Other | “7cc. of autologous PRF are locally administered to the repair site after reconstruction of the rotator cuff” NCT01612845 ↗ |