drugset / Trial / NCT07508033

Evaluation of Stem Cell Exosomes Versus Platelet-Rich Fibrin in Tooth Extraction Socket Healing

NCT07508033

Phase 1/2 Recruiting 40 enrolled Al Salam University
RandomizedParallel-groupSingle-blindTreatment

Summary

This study evaluates two different treatments used to help the jawbone heal after a tooth is removed. When a tooth is extracted, the surrounding bone often shrinks, which can make it difficult to place dental implants later. Currently, doctors often use Platelet-Rich Fibrin (PRF), which is made from the patient's own blood, to help the area heal. This research compares PRF to a newer treatment using "exosomes" derived from stem cells. Exosomes are tiny particles that carry signals to tell the body to repair tissue and grow new bone. The goal of this study is to see if these exosomes work better than PRF at keeping the bone strong and thick after an extraction. Researchers will use specialized X-rays (CBCT) to measure the bone three months after the procedure to see which treatment provided better results.

Timeline

Start
2026-01-15
Primary completion
2026-07-15
Completion
2026-08-01

Drugs

EvaluationDrugModalityDoseRoute
Subject MSC-derived exosomes Other / unclassified
Comparator Platelet Concentrate Other / unclassified

Indications