Drugs / Advanced Platelet-Rich Fibrin
last change Jun 2026 re-read 9 days ago

Advanced Platelet-Rich Fibrin

also known as A-PRF

Other / unclassified

Developed for
impacted teeth, multiple · chronic periodontitis
Investigated by
Inonu University · Jagiellonian University · University of Medicine and Pharmacy at Ho Chi Minh City

Trials 3

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 41 trial
Phase 4 NCT05824793 Oct 2019 → Apr 2021 — University of Medicine and Pharmacy at Ho Chi Minh City Completed No outcome recorded
Phase not applicable2 trials
— NCT07835373 Aug 2025 → Jun 2026 impacted teeth, multiple Inonu University Completed No outcome recorded
— NCT07652216 Apr 2024 → Dec 2026 expected dentigerous cyst, impacted teeth, multiple Jagiellonian University Active not recruiting No outcome recorded
Comparator or background therapy3 trials
Phase 4 NCT06190015 Comparator May 2022 → Jan 2024 — University of Belgrade Unknown No outcome recorded
Phase 4 NCT04767243 Comparator Dec 2020 → Feb 2022 bone resorption disease, chronic periodontitis Maharishi Markendeswar University (Deemed to be University) Completed No outcome recorded
— NCT03672669 Comparator Nov 2017 → Mar 2018 — Near East University, Turkey Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as Advanced platelet rich fibrin “The Efficacy of A-PRF+ on Postoperative Outcomes Following Surgical Removal of Impacted Mandibular Third Molars (A-PRF+: Advanced Platelet Rich Fibrin)” NCT05824793 ↗
5

“A-PRF ( Advanced platelet rich fibrin)” NCT04767243 ↗

NCT03672669 ↗

NCT07835373 ↗

NCT07652216 ↗

NCT06190015 ↗

Known as A-PRF “Advanced platelet-rich fibrin (A-PRF) was prepared from autologous venous blood by centrifugation at 1500 rpm for 14 minutes.” NCT07835373 ↗
6

“Application of autologous Advanced Platelet-Rich Fibrin (A-PRF) into the postoperative defect to support regenerative healing” NCT07652216 ↗

“modified formulation of PRF, commonly known as Advanced PRF (A-PRF)” PMID 32360489 ↗ Apr 2020

“Advanced platelet rich fibrin (APRF) clots” NCT06190015 ↗

“Advanced Platelet Rich Fibrin (A-PRF)” NCT03672669 ↗

NCT05824793 ↗

NCT04767243 ↗

Modality Other / unclassified “Advanced Platelet-Rich Fibrin (A-PRF) is an autologous platelet concentrate rich in growth factors” NCT07652216 ↗
Route Other “A-PRF was applied into the tooth socket after mandibular third molar surgery.” NCT03672669 ↗