drugset / Trial / NCT04767243
Regenerative Potential of Advanced Platelet Rich Fibrin and Bioactive Glass (Perioglas®).
RandomizedParallel-groupDouble-blindTreatment
Summary
The aim of this study is to evaluate and compare the regenerative potential of Advanced Platelet Rich Fibrin (A-PRF) and Bioactive Glass (Perioglas®) bone graft in the treatment of intrabony defects in chronic periodontitis patients.
Timeline
- Start
- 2020-12-01
- Primary completion
- 2022-02-18
- Completion
- 2022-03-04
Publications
- Background Ghanaati S, Booms P, Orlowska A, Kubesch A, Lorenz J, Rutkowski J, Landes C, Sader R, Kirkpatrick C, Choukroun J. Advanced platelet-rich fibrin: a new concept for cell-based tissue engineering by means of inflammatory cells. J Oral Implantol. 2014 Dec;40(6):679-89. doi: 10.1563/aaid-joi-D-14-00138.
- Background Mengel R, Schreiber D, Flores-de-Jacoby L. Bioabsorbable membrane and bioactive glass in the treatment of intrabony defects in patients with generalized aggressive periodontitis: results of a 5-year clinical and radiological study. J Periodontol. 2006 Oct;77(10):1781-7. doi: 10.1902/jop.2006.060029.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Advanced Platelet Rich Fibrin | Other / unclassified | — | — |
| Comparator | PHOSPHINE SILANE | Other / unclassified | — | — |