Impact of Sugammadex vs. Neostigmine Reversal on Post-Operative Recovery and Complications

Summary

Sugammadex or neostigmine are given at the end of the surgery to reverse neuro muscular blocking drugs (NMBD). This study will evaluate whether reversal of NMBD with sugammadex is associated with faster recovery than neostigmine resulting in faster discharge from the operating room (OR) in obese patients with OSA undergoing bariatric surgery. Half of the patients in the study will receive sugammadex and the other half of the patients will receive neostigmine.

Timeline

Start

2019-01-14

Primary completion

2021-10-26

Completion

2021-10-26

Publications

• Ajetunmobi O, Wong D, Perlas A, Rajaleelan W, Wang S, Huszti E, Jackson T, Chung F, Wong J. Impact of Sugammadex Versus Neostigmine Reversal on Postoperative Recovery Time in Patients With Obstructive Sleep Apnea Undergoing Bariatric Surgery: A Double-Blind, Randomized Controlled Trial. Anesth Analg. 2025 Mar 1;140(3):568-576. doi: 10.1213/ANE.0000000000007013. Epub 2024 Jun 7.

Drugs

Indications