Comparison of Berberine and Metformin for the Treatment for MS in Schizophrenia Patients

Summary

Berberine is an isoquinoline alkaloid extracted from medicinal herbs, has been demonstrated to produce beneficial effects on diabetes and hyperlipidemia, fewer study reported its modification on lipid metabolism in schizophrenia. Metformin, have been used for metabolic abnormalities in schizophrenia, findings from these studies indicated that they did have some effect,which are still in experimental stage.This study is aim to compare the efficacy and safety of berberine and metformin for preventing metabolic dysfunction in schizophrenia patients.

Timeline

Start

2021-12-01

Primary completion

2023-10-01

Completion

2023-12-01

Drugs

Indications