drugset / Trial / NCT03728894
Oral Sedation With and Without Nitrous Oxide
RandomizedCrossoverTriple-blindTreatment
Summary
Aims: The objective of the current study was to evaluate the effectiveness of oral midazolam-hydroxyzine with/without nitrous oxide. Design: This was a randomized split mouth, cross over and triple-blinded clinical study. Thirty uncooperative healthy children aged six to nine, whose needed dental treatments.
Timeline
- Start
- 2018-11-17
- Primary completion
- 2019-01-06
- Completion
- 2019-01-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nitrous Oxide | Other / unclassified | 50 % | Inhaled |
| Comparator | Hydroxyzine | Small molecule | 10 mg | Oral |
| Comparator | Midazolam | Small molecule | 7.5 mg | Oral |
| Comparator | Oxygen | Other / unclassified | 50 % | Inhaled |
| Comparator | Oxygen | Other / unclassified | 100 % | Inhaled |
Indications
No indication recorded.