drugset / Trial / NCT03731988
Efficacy of Ablative Fractional Laser-assisted Photodynamic Therapy According to the Laser Density for Actinic Keratosis
RandomizedParallel-groupTriple-blindTreatment
Summary
Erbium:yttrium aluminum garnet (Er:YAG) ablative fractional laser-assisted photodynamic therapy (AFL-PDT) has shown significant benefit for the treatment of actinic keratosis(AK). Er:YAG ablative fractional laser ablates the epidermis and dermis without significant thermal injury, creating microscopic ablation zones (MAZ) in the portion of the skin that the laser is applied to. The formed MAZ depends on the laser parameters such as laser depth, laser density and laser passes, which affect the treatment outcome.
Timeline
- Start
- 2017-02-01
- Primary completion
- 2017-10-30
- Completion
- 2018-10-24
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | methyl aminolevulinate | Small molecule | — | Topical |
| Background | Lidocaine | Other / unclassified | — | Topical |
| Background | prilocaine | Small molecule | — | Topical |