drugset / Trial / NCT03731988

Efficacy of Ablative Fractional Laser-assisted Photodynamic Therapy According to the Laser Density for Actinic Keratosis

NCT03731988

Phase 4 Completed 47 enrolled Dong-A University
RandomizedParallel-groupTriple-blindTreatment

Summary

Erbium:yttrium aluminum garnet (Er:YAG) ablative fractional laser-assisted photodynamic therapy (AFL-PDT) has shown significant benefit for the treatment of actinic keratosis(AK). Er:YAG ablative fractional laser ablates the epidermis and dermis without significant thermal injury, creating microscopic ablation zones (MAZ) in the portion of the skin that the laser is applied to. The formed MAZ depends on the laser parameters such as laser depth, laser density and laser passes, which affect the treatment outcome.

Timeline

Start
2017-02-01
Primary completion
2017-10-30
Completion
2018-10-24

Drugs

EvaluationDrugModalityDoseRoute
Subject methyl aminolevulinate Small molecule Topical
Background Lidocaine Other / unclassified Topical
Background prilocaine Small molecule Topical

Indications