drugset / Trial / NCT03824665
Nalbuphine, Fentanyl and no Additive to Local Anaesthetic Mixture
RandomizedParallel-groupDouble-blindSupportive care
Summary
Nalbuphine has been used as an adjuvant to bupivacaine in intrathecal,epidural, caudal anesthesia and peripheral nerve blocks showing an increase in the efficacy and the duration of postoperative analgesia. The aim of this study is evaluation of the effect of 4 mg Nalbuphine when used as an adjuvant to a local anesthetic mixture in peribulbar block undergoing posterior chamber surgery in adult patients and comparing it with adding Fentanyl 20 μg to LAM and LAM alone
Timeline
- Start
- 2019-02-05
- Primary completion
- 2019-05-10
- Completion
- 2019-05-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fentanyl | Other / unclassified | 20 ug | Other |
| Comparator | Nalbuphine | Small molecule | 4 mg | Other |
| Background | Bupivacaine | Other / unclassified | 0.5 % | Other |
| Background | Bupivacaine | Other / unclassified | 6 ml | Other |
| Background | rHuPH20 | Protein / enzyme biologic | 150 iu | Other |
Indications
No indication recorded.