drugset / Trial / NCT03841591
Maternal Weight Gain in Gestational Diabetes Controlled by Metformin Versus Insulin
RandomizedParallel-groupOpen-labelOther
Summary
Insulin has many disadvantages for mothers with GDM including the need to give injections, frequent daily testing for monitoring, and risks of hypoglycemia, increase in appetite, weight gain and high cost. Metformin, an oral biguanide, may be a more logical alternative to insulin for women with GDM who are unable to cope with the increasing insulin resistance of pregnancy. This study aim to compare maternal weight gain during pregnancy in women with gestational diabetes, treated by insulin versus metformin.
Timeline
- Start
- 2018-02-01
- Primary completion
- 2018-12-25
- Completion
- 2019-01-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Insulin | Protein / enzyme biologic | 30 unknown | Other |
| Comparator | Metformin | Small molecule | 2500 mg | Oral |