drugset / Trial / NCT03841591

Maternal Weight Gain in Gestational Diabetes Controlled by Metformin Versus Insulin

NCT03841591

Phase 3 Completed 124 enrolled Ain Shams University
RandomizedParallel-groupOpen-labelOther

Summary

Insulin has many disadvantages for mothers with GDM including the need to give injections, frequent daily testing for monitoring, and risks of hypoglycemia, increase in appetite, weight gain and high cost. Metformin, an oral biguanide, may be a more logical alternative to insulin for women with GDM who are unable to cope with the increasing insulin resistance of pregnancy. This study aim to compare maternal weight gain during pregnancy in women with gestational diabetes, treated by insulin versus metformin.

Timeline

Start
2018-02-01
Primary completion
2018-12-25
Completion
2019-01-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Insulin Protein / enzyme biologic 30 unknown Other
Comparator Metformin Small molecule 2500 mg Oral

Indications