drugset / Trial / NCT03954379

IPACK Study in Total Knee Arthroplasty Patients

NCT03954379 ↗

Phase 4 Completed 78 enrolled University Health Network, Toronto
RandomizedParallel-groupDouble-blindTreatment

Summary

This study proposes to compare current multimodal analgesic treatment for TKA with a new multimodal analgesic regimen to demonstrate decreased opioid requirement, time to rehabilitation, and time to reach hospital discharge.

Timeline

Start
2019-10-24
Primary completion
2020-12-02
Completion
2021-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified — Intravenous
Subject Ketamine Small molecule — Intravenous
Background Dexamethasone Small molecule 8 mg Intravenous
Comparator Propofol Small molecule — Intravenous

Indications

No indication recorded.