A Clinical Study to Assess the Effects of Various Dentifrice Technologies on Dentinal Hypersensitivity

Summary

The objective of this study is to evaluate the efficacy (changes in dentinal hypersensitivity) and safety (oral soft tissue evaluation) after use of one of four dentifrices in subjects with pre-existing hypersensitivity over an 11-week period.

Timeline

Start

2019-07-08

Primary completion

2019-10-03

Completion

2019-10-03

Publications

• Biesbrock AR, He T, Zou Y, Grender JM, Amini P, Sagel PA, Groth A, Klukowska M. Randomized clinical trial evaluating kinetic benefits of desensitizing agents: Magnitude, onset, and stability of relief. J Periodontol. 2025 Dec;96(12):1339-1351. doi: 10.1002/JPER.24-0688. Epub 2025 May 30.

Drugs

Indications