drugset / Trial / NCT03979820
A Study in Healthy People to Test How Combining BI 1467335 and Tyramine Affects Blood Pressure
RandomizedParallel-groupDouble-blindTreatment
Summary
The main objective of the study is investigate the effect of escalating doses of oral tyramine on systolic blood pressure (SBP) at baseline and following an oral treatment with BI 1467335 up to 39 days at a low or high dose once daily compared to placebo and phenelzine (Nardil®) as positive control.
Timeline
- Start
- 2019-07-31
- Primary completion
- 2020-04-08
- Completion
- 2020-04-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | BI 1467335 | Unknown | 10 mg | — |
| Subject | BI 1467335 | Unknown | 15 mg | — |
| Comparator | Phenelzine | Small molecule | — | — |
| Subject | Tyramine | Small molecule | — | — |
Indications
No indication recorded.