drugset / Trial / NCT03999125
Anti-VEGF Therapy Versus Dexamethasone Implant for DME
RandomizedParallel-groupDouble-blindTreatment
Summary
We look at a randomized comparative study of 2 FDA approved anti-VEGF agents(aflibercept and ranibizumab) and see how they compare against the dexamethasone implant for phakic as well as pseudophakic eyes with treatment naive diabetic macular edema in terms of efficacy and safety over two years.
Timeline
- Start
- 2019-06-25
- Primary completion
- 2021-06-24
- Completion
- 2023-06-24
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Aflibercept | Protein / enzyme biologic | — | Intravitreal |
| Subject | Dexamethasone | Small molecule | — | Intravitreal |
| Subject | Ranibizumab | Monoclonal antibody | — | Intravitreal |