drugset / Trial / NCT03999125

Anti-VEGF Therapy Versus Dexamethasone Implant for DME

NCT03999125

Phase 4 Unknown 150 enrolled Sudhalkar Eye Hospital
RandomizedParallel-groupDouble-blindTreatment

Summary

We look at a randomized comparative study of 2 FDA approved anti-VEGF agents(aflibercept and ranibizumab) and see how they compare against the dexamethasone implant for phakic as well as pseudophakic eyes with treatment naive diabetic macular edema in terms of efficacy and safety over two years.

Timeline

Start
2019-06-25
Primary completion
2021-06-24
Completion
2023-06-24

Drugs

EvaluationDrugModalityDoseRoute
Comparator Aflibercept Protein / enzyme biologic Intravitreal
Subject Dexamethasone Small molecule Intravitreal
Subject Ranibizumab Monoclonal antibody Intravitreal