drugset / Trial / NCT04048200

The Effect of Opioid Free Anesthesia in Bariatric Surgeries

NCT04048200 ↗

Phase 4 Completed 90 enrolled Tanta University
RandomizedParallel-groupTriple-blindSupportive care

Summary

This is a prospective randomized controlled study that will be carried out on morbid obese patients admitted to Tanta University hospitals for laparoscopic bariatric surgeries. The patients will be randomly assigned into;- Control group:- Anesthesia will be induced by fentanyl 1 ug/kg, propofol 2 mg/kg, and rocuronium 1 mg/kg to facilitate tracheal intubation. Anesthesia will be maintained by sevoflurane 2% in a mixture of oxygen: Air 1: 1 to maintain entropy 40-60. Opioid free anesthesia group;- Anesthesia will be induced by propofol 2 mg/kg, rocuronium 1 mg/kg to facilitate tracheal intubation. After endotracheal intubation, and a combination of dexmedetomidine and ketamine infusion. Anesthesia will be maintained by sevoflurane 2% in a mixture of oxygen: Air 1: 1 and continuing the infusion of dexmedetomidine and ketamine o maintain entropy 40-60.

Timeline

Start
2019-09-01
Primary completion
2020-06-15
Completion
2020-06-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexmedetomidine Other / unclassified — —
Subject Fentanyl Other / unclassified 1 ug/kg —
Subject Ketamine Small molecule — —

Indications

No indication recorded.