drugset / Trial / NCT04148599

Effect of IV Infusion of Lidocaine Compared to IV Infusion of Dexmedetomidine on Proinflammatory Cytokines

NCT04148599

RandomizedParallel-groupDouble-blindPrevention

Summary

This study is designed to compare between intravenous infusion of dexmedetomidine and intravenous infusion of lidocaine in reduction of proinflammatory cytokines as IL-6 and TNF-α, some stress reactions (serum insulin and serum lactate),and postoperative analgesic requirements in patients undergoing surgery for pelviabdominal cancers.

Timeline

Start
2018-01-02
Primary completion
2020-06-10
Completion
2020-06-13

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexmedetomidine Other / unclassified 0.5 ug/kg Intravenous
Comparator Lidocaine Other / unclassified 1.5 mg/kg Intravenous

Indications