drugset / Trial / NCT04150614
BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron
RandomizedParallel-groupOpen-labelSupportive care
Summary
Patients undergoing either an autologous or allogeneic hematopoietic stem cell transplant (HSCT) and receiving preparative chemotherapy experience a considerable amount of chemotherapy-induced nausea and vomiting (CINV). Current strategies at reducing CINV in this patient population are suboptimal due to lack of efficacy and supportive evidence, potential for increased adverse events, and drug-drug and drug-disease contraindications.
Timeline
- Start
- 2020-05-14
- Primary completion
- 2026-07
- Completion
- 2026-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Granisetron | Other / unclassified | — | Other |
| Comparator | Ondansetron | Other / unclassified | — | Intravenous |
| Comparator | Dexamethasone | Small molecule | — | Intravenous |