drugset / Trial / NCT04162015
A Study of Nivolumab and Chemotherapy Followed by Surgery for Mesothelioma
Phase 1
Active not recruiting
22 enrolled
Memorial Sloan Kettering Cancer Center
Bristol-Myers Squibb · collab
NaSingle-groupOpen-labelTreatment
Summary
This study will test whether giving nivolumab in combination with pemetrexed and either cisplatin or carboplatin before surgery is a safe and effective approach to treating resectable mesothelioma without delaying surgery.
Timeline
- Start
- 2019-11-12
- Primary completion
- 2026-11
- Completion
- 2026-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carboplatin | Small molecule | 5 unknown | — |
| Subject | Cisplatin | Other / unclassified | 75 mg/m2 | — |
| Subject | Nivolumab | Monoclonal antibody | 360 mg | — |
| Subject | Pemetrexed | Small molecule | 500 mg/m2 | — |