drugset / Trial / NCT04197115

Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis

NCT04197115

Phase 3 Completed 19 enrolled IMSS Hospital General de Zona 11, Piedras Negras
Non-randomizedSequentialOpen-labelTreatment

Summary

Prospective, experimental, longitudinal cohort study in septic patients treated at ER and ICU at General Hospital Zone 11 IMSS Piedras Negras Coahuila. Interventions, will be implementd in 2 consecutive periods of 6 months Phase 1: 6 months period, septic patients treated only with standard treatment. Phase 2: 6 months period, septic patients treated with Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone + standard treatment.

Timeline

Start
2019-09-01
Primary completion
2020-08-30
Completion
2020-09-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Hydrocortisone Other / unclassified 50 mg Intravenous
Comparator Pyridoxine Unknown 5 mg Other
Comparator Thiamine Other / unclassified 100 mg Other
Comparator Vitamin B12 Other / unclassified 50 ug Other
Comparator Vitamin C Other / unclassified 1.5 g Intravenous