drugset / Trial / NCT04222348

MeDiGes Study: Metformine Use in Gestational Diabetes

NCT04222348

RandomizedParallel-groupOpen-labelTreatment

Summary

Women with gestational diabete (GD) who do not meet glycemic control objectives with diet will be assigned to two treatment groups randomly. One: metformin at a dose of 850-2550mg every 24h; two: insulin detemir associated or not with rapid insulin analogue (aspart) according to your glycemic controls. The Metformin group may additionally receive insulin in a second time in case the glycemic control is not appropriate with monotherapy.

Timeline

Start
2016-10-26
Primary completion
2020-05-28
Completion
2020-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Metformin Small molecule 850 mg
Subject Metformin Small molecule 2550 mg
Subject insulin detemir Protein / enzyme biologic