drugset / Trial / NCT04243109

Study of Pomalidomide, Oral Dexamethasone and Very Low-dose Cyclophosphamide in Patients With Refractory Multiple Myeloma Who Have Received Lenalidomide and Bortezomib

NCT04243109

NaSingle-groupOpen-labelTreatment

Summary

Clinical trial with a pharmaceutical specialty in a new combination. Pomalidomide in combination with dexamethasone is indicated in the treatment of adult patients with multiple treatment-resistant or relapsing myeloma who have received at least two previous treatments, including lenalidomide and bortezomib, and who have experienced a disease progression in the last treatment. The combination of Pomalidomide with Cyclophosphamide at metronomic doses (Very low doses) and Dexamethasone is tested in this clinical situation.

Timeline

Start
2017-02-23
Primary completion
2019-05-07
Completion
2019-05-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyclophosphamide Other / unclassified 15 mg
Subject Dexamethasone Small molecule 20 mg
Subject Dexamethasone Small molecule 40 mg
Subject Pomalidomide Other / unclassified 4 mg

Indications