drugset / Trial / NCT04243109
Study of Pomalidomide, Oral Dexamethasone and Very Low-dose Cyclophosphamide in Patients With Refractory Multiple Myeloma Who Have Received Lenalidomide and Bortezomib
NaSingle-groupOpen-labelTreatment
Summary
Clinical trial with a pharmaceutical specialty in a new combination. Pomalidomide in combination with dexamethasone is indicated in the treatment of adult patients with multiple treatment-resistant or relapsing myeloma who have received at least two previous treatments, including lenalidomide and bortezomib, and who have experienced a disease progression in the last treatment. The combination of Pomalidomide with Cyclophosphamide at metronomic doses (Very low doses) and Dexamethasone is tested in this clinical situation.
Timeline
- Start
- 2017-02-23
- Primary completion
- 2019-05-07
- Completion
- 2019-05-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclophosphamide | Other / unclassified | 15 mg | — |
| Subject | Dexamethasone | Small molecule | 20 mg | — |
| Subject | Dexamethasone | Small molecule | 40 mg | — |
| Subject | Pomalidomide | Other / unclassified | 4 mg | — |