drugset / Trial / NCT04245774

Comparing the Effects of Levobupivacaine and Bupivacaine in Saddle Spinal Anesthesia

NCT04245774

Phase 4 Completed 60 enrolled Gazi University
RandomizedParallel-groupQuadruple-blindOther

Summary

İn this study; it was aimed to investigate the effects of equipotent doses of hyperbaric bupivacaine and hyperbaric levobupivacaine in outpatient anorectal surgery under saddle block. Sixty patients between the age of 18- 50 and in the risk group of ASA I-II included in the study. 7,5 mg of 0,5% hyperbaric bupivacaine or 7,5 mg of 0,5% hyperbaric levobupivacaine injected into the intrathecal space in sitting position through L4-L5 or L5-S1 intervertebral space in 30 seconds. All patients kept in sitting position for 5 minutes with aid after intrathecal injection and than layed in supine position, finally they positioned in prone jack-knife. Hemodynamic parameters like NIBP, HR, SpO2, sensory and motor block characteristics, duration of analgesia, time of first voiding, mobilization time, patient and surgeon satisfaction, adverse effects and discharge time were recorded during and after surgery.

Timeline

Start
2007-11-21
Primary completion
2008-08-13
Completion
2008-12-17

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bupivacaine Other / unclassified 7.5 mg
Subject Levobupivacaine Other / unclassified 7.5 mg Intrathecal

Indications