Norepinephrine / Vasopressin Combination for Resuscitation in Septic Shock

Summary

Although norepinephrine is commonly used and is the recommended agent for the treatment of hypotension in volume-resuscitated hyperdynamic septic shock, Low doses of vasopressin may be added to norepinephrine to maintain arterial blood pressure in refractory septic shock and to decrease exposure to norepinephrine. The aim of the work is to compare the effect of norepinephrine alone and Norepinephrine/vasopressin combination on hemodynamics and tissue perfusion in septic shock patients.

Timeline

Start

2018-01-01

Primary completion

2019-01-05

Completion

2019-01-06

Drugs

Indications