drugset / Trial / NCT04332627
Comparison of QoR-15 in Laparoscopic Cholecystectomy: Sugammadex vs. Neostigmine
RandomizedParallel-groupTriple-blindOther
Summary
The quality of recovery in patients who were reversed neuromuscular blockade by using Sumamadex and Neostigmine in laparoscopic cholecystectomy was compared through the QoR(Quality of Recovery)-15 questionnaire.
Timeline
- Start
- 2020-02-24
- Primary completion
- 2020-05-21
- Completion
- 2020-05-21
Publications
- Background Stark PA, Myles PS, Burke JA. Development and psychometric evaluation of a postoperative quality of recovery score: the QoR-15. Anesthesiology. 2013 Jun;118(6):1332-40. doi: 10.1097/ALN.0b013e318289b84b.
- Background Hristovska AM, Duch P, Allingstrup M, Afshari A. Efficacy and safety of sugammadex versus neostigmine in reversing neuromuscular blockade in adults. Cochrane Database Syst Rev. 2017 Aug 14;8(8):CD012763. doi: 10.1002/14651858.CD012763.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Neostigmine | Other / unclassified | 0.02 mg/kg | — |
| Comparator | Neostigmine | Other / unclassified | 0.04 mg/kg | — |
| Comparator | Neostigmine | Other / unclassified | 0.05 mg/kg | — |
| Comparator | Sugammadex | Other / unclassified | 2 mg/kg | — |
| Comparator | Sugammadex | Other / unclassified | 4 mg/kg | — |
| Comparator | Glycopyrrolate | Small molecule | 0.4 mg | — |