drugset / Trial / NCT04367103

Norepinephrine for Hypotension in Cesarean Section

NCT04367103

Completed 180 enrolled Assiut University
RandomizedParallel-groupTriple-blindPrevention

Summary

Hypotension is a very common consequence of the sympathetic vasomotor block caused by spinal anesthesia for cesarean section. Maternal symptoms such as nausea, vomiting and dyspnea frequently accompany severe hypotension, and adverse effects on the fetus, including depressed APGAR scores and umbilical acidosis, have been correlated with severity and duration of hypotension. Because hypotension is frequent, vasopressors should be used routinely and preferably prophylactically.

Timeline

Start
2021-04-10
Primary completion
2022-05-04
Completion
2022-05-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Norepinephrine Other / unclassified 0.025 ug/kg
Comparator Phenylephrine Small molecule 25 ug

Indications