Optimal Anesthesia for Morbidly Obese Patients

Summary

Obese patients have a higher risk of anesthesia compared to the non-obese, including difficult intubation, rapid desaturation, difficult vascular access, and delayed recovery from anesthesia. This study aims to investigate the optimal anesthesia strategy for morbidly obese patients undergoing bariatric surgery in airway management, preoxygenation, arterial cannulation, and type of volatile anesthetic with M-Entropy guidance. The investigators will conduct a two-year clinical trial using permuted block randomization to evaluate multiple outcomes in patients undergoing laparoscopic sleeve gastrectomy (LSG) at Shuang Ho Hospital, Taipei Medical University. Particularly, the investigators will explore the role of ultrasound, an easily accessible modality for anesthesiologists, in examining upper airway anatomy and guiding arterial cannulation. The investigators will also assess the effectiveness of high-flow nasal cannula as a preoxygenation tool in preventing desaturation.

Timeline

Start

2020-05-26

Primary completion

2021-08-31

Completion

2021-08-31

Publications

• Wu YM, Su YH, Huang SY, Wang CW, Shen SC, Chen JT, Lo PH, Cherng YG, Wu HL, Tai YH. Morphometric and ultrasonographic determinants of difficult laryngoscopy in obese patients: A prospective observational study. J Chin Med Assoc. 2022 May 1;85(5):571-577. doi: 10.1097/JCMA.0000000000000721. Epub 2022 May 2.

Drugs

Indications