drugset / Trial / NCT04410887

Neoadjuvant Chemotherapy With PISOXO for Locally-invaded-gastric Cancer (LIGC)

NCT04410887

Phase 1/2 Unknown 30 enrolled Ruijin Hospital
NaSingle-groupOpen-labelTreatment

Summary

The main purpose of this study is to compare the safety and efficacy of PIPAC+SOX+OLAPARIB for locally-invaded-gastric cancer (LIGC) patients in China. To obtain preliminary results for designing a new phase II/III randomized controlled trial.

Timeline

Start
2020-12
Primary completion
2021-12
Completion
2022-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Docetaxel Small molecule Other
Subject Olaparib Small molecule 300 mg Oral
Subject Oxaliplatin Small molecule 130 mg/m2 Intravenous
Subject S-1 Small molecule 80 mg/m2 Oral

Indications