drugset / Trial / NCT04417699

SHOrt Course Radiation and TASOX (TAS102 Plus Oxaliplatin) Chemotherapy in Operable Rectal Cancer

NCT04417699

NaSingle-groupOpen-labelTreatment

Summary

TASOX can be safely and efficaciously delivered after short course radiation, resulting in significant pathologic downstaging, allowing for an R0 pelvic resection, and providing local control in appropriately selected stage II/III rectal cancer patients treated with contemporary TME-based surgery.

Timeline

Start
2022-07-05
Primary completion
2023-12-14
Completion
2024-02-21

Drugs

EvaluationDrugModalityDoseRoute
Subject Oxaliplatin Small molecule 85 mg/m2 Intravenous
Subject TAS-102 Small molecule 35 mg/m2 Oral

Indications