drugset / Trial / NCT04418908
Estrogen, Diabetes, and Endothelial Function
RandomizedParallel-groupQuadruple-blindBasic science
Summary
This study planned to learn more about women and how the drop in estradiol levels during menopause may affect their cardiovascular risk. With aging, the arteries that are located around the heart get stiffer, and this increase in arterial stiffness can lead to a number of health problems such as high blood pressure and heart disease. In this study, the investigators examined whether a short-term drop in estrogen levels caused arteries to become stiffer, and explored potential reasons for stiffening arteries.
Timeline
- Start
- 2010-11-24
- Primary completion
- 2018-10-22
- Completion
- 2018-10-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Estradiol | Other / unclassified | 0.025 mg | Other |
| Comparator | Estradiol | Other / unclassified | 0.075 mg | Other |
| Comparator | Cetrorelix | Other / unclassified | 0.25 mg | Subcutaneous |