drugset / Trial / NCT04436224
Hydromorphone for ICU-analgesia in Patients With Non-mechanical Ventilation
RandomizedParallel-groupOpen-labelTreatment
Summary
Hydromorphone has a clear analgesic effect, and has few advantages in respiratory depression and gastrointestinal motility. The study will further explore the continuous pumping-dose of hydromorphone for ICU non-mechanical ventilation patients and monitor its effective plasma concentration as well as evaluates the safety and effectiveness of hydromorphone for ICU non-mechanical ventilation patients.
Timeline
- Start
- 2020-09-04
- Primary completion
- 2022-06
- Completion
- 2022-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Butorphanol | Other / unclassified | 0.7 mg/kg | Intravenous |
| Comparator | Butorphanol | Other / unclassified | 10 mg/kg | Intravenous |
| Comparator | Fentanyl | Other / unclassified | 0.08 mg | Intravenous |
| Comparator | Fentanyl | Other / unclassified | 0.2 mg | Intravenous |
| Subject | Hydromorphone | Other / unclassified | 0.5 mg | Intravenous |
Indications
No indication recorded.