drugset / Trial / NCT04457050
Effect of Hepatitis C Clearance on Insulin Resistance
NaSingle-groupOpen-labelTreatment
Summary
Chronic hepatitis C infection has been linked to insulin resistance, which is the essential component of metabolic syndrome and type 2 diabetes mellitus. Resistin; an adipokine, has been demonstrated to stimulate the secretion of several inflammatory factors known to play a role in the induction of insulin resistance. we investigated the changes in insulin resistance after hepatitis C clearance in the era of direct antivirals.
Timeline
- Start
- 2017-10-30
- Primary completion
- 2019-11-01
- Completion
- 2019-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Daclatasvir | Small molecule | 60 mg | — |
| Subject | Ledipasvir | Small molecule | 90 mg | — |
| Subject | Ribavirin | Small molecule | 1000 mg | — |
| Subject | Ribavirin | Small molecule | 1200 mg | — |
| Subject | Sofosbuvir | Small molecule | 400 mg | — |