drugset / Trial / NCT04498351

Magnesium Sulfate in Combination With Dexmedetomidine As Adjuvants to Levobupivacaine

NCT04498351

Phase 0 Completed 130 enrolled Cairo University
RandomizedParallel-groupTriple-blindDiagnostic

Summary

Using the spermatic cord block has been of great advantage, as it has been cost saving, efficient technique whether used inon its own or combination with a sedative or . Furthermore, it provides minimal cardiac risks, early case ambulation, satisfactory postoperative pain control, as well as a reduced hospital stay and cost. one of the major drawbacks of spermatic cord block is being a single injection technique, leading to a short postoperative analgesia duration. So, to overcome this flaw some adjuvants were proven to prolong the analgesia duration as Dexmetedomidine (Dex), and magnesium.

Timeline

Start
2020-06-30
Primary completion
2021-09-20
Completion
2021-10-22

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexmedetomidine Other / unclassified 1 ug/kg
Comparator Magnesium Sulfate Other / unclassified 100 mg
Comparator Levobupivacaine Other / unclassified 0.5 %
Comparator Levobupivacaine Other / unclassified 18 ml

Indications

No indication recorded.