drugset / Trial / NCT04501861

Hemodynamic Effect of Norepinephrine Versus Vasopressin on the Pulmonary Circulation in Cardiac Surgery Patients:

NCT04501861

Phase 3 Completed 153 enrolled The Cleveland Clinic
RandomizedCrossoverOpen-labelTreatment

Summary

The relative increase in the mPAP with the same unit increase in MAP adjusted for baseline, and RV function assessed by GLS, between VP and NE in patients with normal and increased pulmonary artery pressure, who require vasopressor support during cardiac surgery.

Timeline

Start
2020-11-05
Primary completion
2023-08-22
Completion
2024-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Norepinephrine Other / unclassified 4 mg
Comparator Vasopressin Peptide 20 iu

Indications