drugset / Trial / NCT04501861
Hemodynamic Effect of Norepinephrine Versus Vasopressin on the Pulmonary Circulation in Cardiac Surgery Patients:
RandomizedCrossoverOpen-labelTreatment
Summary
The relative increase in the mPAP with the same unit increase in MAP adjusted for baseline, and RV function assessed by GLS, between VP and NE in patients with normal and increased pulmonary artery pressure, who require vasopressor support during cardiac surgery.
Timeline
- Start
- 2020-11-05
- Primary completion
- 2023-08-22
- Completion
- 2024-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Norepinephrine | Other / unclassified | 4 mg | — |
| Comparator | Vasopressin | Peptide | 20 iu | — |