drugset / Trial / NCT04530422

Efficacy of Sofosbuvir Plus Ledipasvir in Egyptian Patients With COVID-19 Compared to Standard Treatment

NCT04530422

Phase 3 Completed 250 enrolled Almaza Military Fever Hospital
RandomizedParallel-groupSingle-blindTreatment

Summary

Currently there is no known effective therapy or vaccine for treatment of SARS-CoV-2, highlighting urgency around identifying effective therapies. This study aiming to evaluate the anti-HCV medications efficacy "Sofosbuvir-Ledipasvir" in treatment of moderate cases with SARS-COV-2 infection, in comparison to the standard treatment (hydroxychloroquine, oseltamivir and azithromycin).

Timeline

Start
2020-04-15
Primary completion
2020-07-08
Completion
2020-07-23

Drugs

EvaluationDrugModalityDoseRoute
Subject Azithromycin Small molecule 250 mg
Subject Hydroxychloroquine Small molecule 200 mg
Subject Ledipasvir Small molecule
Subject Oseltamivir Small molecule 150 mg
Subject Sofosbuvir Small molecule

Indications