drugset / Trial / NCT04541732

Postoperative Analgesia of Quadratus Lumborum Block Versus Epidural Block After Major Abdominal Surgeries

NCT04541732

Completed 80 enrolled Mansoura University
RandomizedParallel-groupSingle-blindPrevention

Summary

Acute postoperative pain is an important issue after major abdominal surgeries for which different analgesic modalities have been tried. Epidural analgesia is the recommended technique to relieve pain after major abdominal surgeries owing to the proved superior analgesia, reduction of opioid-related side effects as nausea, vomiting, pruritis and sedation, earlier recovery of bowel function and earlier ability for postoperative mobility. However, it is not without complications. Quadratus lumborum block is an ultrasound-guided block that provides patients with both visceral and somatic blockade. It lessens the potential risks associated with neuraxial techniques, so it may represent a novel alternative approach for analgesia after major abdominal surgeries.

Timeline

Start
2019-01-01
Primary completion
2019-04-09
Completion
2019-05-06

Drugs

EvaluationDrugModalityDoseRoute
Background Atracurium Small molecule 0.5 mg/kg
Background Propofol Small molecule 1.5 mg/kg
Background Propofol Small molecule 2.5 mg/kg
Background Sevoflurane Other / unclassified 0.7 unknown
Background Sevoflurane Other / unclassified 1.5 unknown

Indications

No indication recorded.