drugset / Trial / NCT04544228
Ketamine or Neostigmine for Serratus Anterior Plane Block in Modified Radical Mastectomy
RandomizedParallel-groupTriple-blindTreatment
Summary
The aim of this study is to Investigate the analgesic efficacy of adding ketamine compared to neostigmine to local anesthetic in Ultrasound guided Serratus anterior plane block for patients undergoing Modified Radical Mastectomy.
Timeline
- Start
- 2020-09-05
- Primary completion
- 2021-02-20
- Completion
- 2021-03-01
Publications
- Background El Mourad MB, Amer AF. Effects of adding dexamethasone or ketamine to bupivacaine for ultrasound-guided thoracic paravertebral block in patients undergoing modified radical mastectomy: A prospective randomized controlled study. Indian J Anaesth. 2018 Apr;62(4):285-291. doi: 10.4103/ija.IJA_791_17.
- Background Pandey V, Mohindra BK, Sodhi GS. Comparative evaluation of different doses of intrathecal neostigmine as an adjuvant to bupivacaine for postoperative analgesia. Anesth Essays Res. 2016 Sep-Dec;10(3):538-545. doi: 10.4103/0259-1162.180779.
- Background Blanco R, Parras T, McDonnell JG, Prats-Galino A. Serratus plane block: a novel ultrasound-guided thoracic wall nerve block. Anaesthesia. 2013 Nov;68(11):1107-13. doi: 10.1111/anae.12344. Epub 2013 Aug 7.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketamine | Small molecule | 50 mg | — |
| Subject | Neostigmine | Other / unclassified | 500 ug | — |
| Background | Bupivacaine | Other / unclassified | 0.25 % | — |
| Background | Bupivacaine | Other / unclassified | 30 ml | — |
Indications
No indication recorded.