drugset / Trial / NCT04547049
A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies
RandomizedParallel-groupOpen-labelTreatment
Summary
An open, multi-center, randomized trial comparing haploidentical HSCTs from young non-first-degree and older first-degree donors in hematological malignancies
Timeline
- Start
- 2020-09-01
- Primary completion
- 2026-04-01
- Completion
- 2026-04-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Busulfan | Small molecule | 3.2 mg/kg | Intravenous |
| Comparator | Cyclophosphamide | Other / unclassified | 1.8 g | Intravenous |
| Comparator | Cyclosporine | Peptide | 2.5 mg/kg | Intravenous |
| Comparator | Cytarabine | Small molecule | 4 mg/m2 | Intravenous |
| Comparator | MTX | Unknown | 10 mg/m2 | Intravenous |
| Comparator | Me-CCNU | Unknown | 250 mg/m2 | Oral |
| Comparator | Mycophenolate Mofetil | Small molecule | 500 mg | Intravenous |
| Comparator | Thymoglobulin | Protein / enzyme biologic | 6 mg/kg | Intravenous |
| Comparator | Thymoglobulin | Protein / enzyme biologic | 7.5 mg/kg | Intravenous |