drugset / Trial / NCT04566796
Effectiveness of Sugammadex on Muscle Relaxant Reversal in Preterm Neonates
RandomizedParallel-groupDouble-blindTreatment
Summary
The primary aim of the work is to compare the efficacy of Sugammadex and neostigmine in reversing rocuronium-induced muscle relaxation to reach complete recovery of neuromuscular block (TOF ratio≥ 0.9) in preterm neonates. The secondary aim is to evaluate the safety of using Sugammadex in preterm neonates and to detect any complications that may occur in this age group.
Timeline
- Start
- 2020-08-11
- Primary completion
- 2021-02
- Completion
- 2021-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Neostigmine | Other / unclassified | 0.05 mg/kg | Intravenous |
| Subject | Sugammadex | Other / unclassified | 2 mg/kg | Intravenous |
| Comparator | Atropine | Other / unclassified | 0.02 mg/kg | Intravenous |
Indications
No indication recorded.