drugset / Trial / NCT04608981
Effect of Diclofenac Potassium Versus Prednisolone on Post-endodontic Pain and Pulpal IL-8 Expression
RandomizedParallel-groupQuadruple-blindTreatment
Summary
To assess the effect of using diclofenac potassium versus prednisolone as a pre-medication compared to placebo on: * Intensity of post-endodontic pain in patients with symptomatic irreversible pulpitis. * Pulpal IL-8 expression. * Incidence of post-endodontic pain in patients with symptomatic irreversible pulpitis.
Timeline
- Start
- 2021-03
- Primary completion
- 2021-12
- Completion
- 2022-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Diclofenac | Other / unclassified | 50 mg | Oral |
| Subject | Prednisolone | Other / unclassified | 30 mg | Oral |