Spinal Fentanyl or Epidural Analgesia in the Early First Phase of Induced Labor

Phase 4 Completed 60 enrolled Women's Hospital HUS

RandomizedParallel-groupTriple-blindTreatment

Summary

A total of 60 parturients undergoing induction of labour will be consented to participate in the study where they will be randomized to receive either spinal fentanyl (20 µg) or epidural analgesia (fentanyl 100µg and lidocaine 80 mg). They will be monitored for the development of analgesia for a duration of 30 minutes.

Timeline

Start: 2021-03-26
Primary completion: 2023-05-19
Completion: 2023-05-19

Publications

Background Salmi L, Jernman R, Vaananen A. Is epidural analgesia non-inferior to intrathecal fentanyl as initiation for neuraxial analgesia in early non-spontaneous labour? Acta Anaesthesiol Scand. 2024 May;68(5):664-674. doi: 10.1111/aas.14389. Epub 2024 Feb 16.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Fentanyl	Other / unclassified	20 ug	Intrathecal
Subject	Fentanyl	Other / unclassified	100 ug	Intrathecal
Subject	Lidocaine	Other / unclassified	80 mg	Other

Indications

No indication recorded.