drugset / Trial / NCT04659057
Nebulized Lidocaine, Dexmedetomedine and Their Combination in Direct Laryngoscopy Surgery
RandomizedParallel-groupTriple-blindPrevention
Summary
Direct laryngoscopy (DL) procedure is typically done under general anaesthesia as a day case. It is a short but irritating.Various drugs and drug combinations have been used to attenuate stress response to DL.Administrating nebulized form of drugs can be effective with less systemic side effects. The primary outcome of this study is to compare the effect of premedication with nebulized lidocaine, dexmedetomidine, combination of both to placebo on haemodynamic response during DL procedures.
Timeline
- Start
- 2020-12-12
- Primary completion
- 2021-07-11
- Completion
- 2021-07-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexmedetomidine | Other / unclassified | 0.5 ug/kg | Other |
| Comparator | Dexmedetomidine | Other / unclassified | 1 ug/kg | Other |
| Comparator | Lidocaine | Other / unclassified | 0.5 mg/kg | Other |
| Comparator | Lidocaine | Other / unclassified | 1 mg/kg | Other |
Indications
No indication recorded.