drugset / Trial / NCT04668976
A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma
Phase 2
Unknown
100 enrolled
Benaroya Research Institute
Virginia Mason Hospital/Medical Center · collab
NaSingle-groupOpen-labelTreatment
Summary
This study is being done to answer the following question: Is the combination of the Medtronic pump and the Codman catheter device a safe alternative to the C3000 Codman pump for delivering chemotherapy directly into the liver of patients with metastatic colorectal cancer or cholangiocarcinoma?
Timeline
- Start
- 2020-11-25
- Primary completion
- 2023-12
- Completion
- 2024-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Cetuximab | Monoclonal antibody | — | — |
| Background | Floxuridine | Unknown | — | — |
| Background | Gemcitabine | Small molecule | 800 mg/m2 | Intravenous |
| Background | Gemcitabine | Small molecule | 1000 mg/m2 | Intravenous |
| Background | Irinotecan | Small molecule | — | — |
| Background | Oxaliplatin | Small molecule | 85 mg/m2 | Intravenous |
| Background | Panitumumab | Monoclonal antibody | — | — |
| Background | fluorouracil | Small molecule | — | — |