drugset / Trial / NCT04798391

Effectiveness of Intratympanic Dexamethasone With Ligmocaine for Alleviation of Tinnitus

NCT04798391 ↗

Phase 4 Unknown 264 enrolled Combined Military Hospital, Pakistan
NaSingle-groupOpen-labelTreatment

Summary

Objective: To determine the effectiveness of Intratympanic dexamethasone with lignocaine in control of idiopathic tinnitus. Methodology: 264 consenting patients with idiopathic unilateral tinnitus presenting at ENT Department were assessed for tinnitus severity using Modified Tinnitus Handicap Inventory and the scores recorded and subsequently administered intratympanically 2.0 ml (milliliter's) of dexamethasone and lignocaine (1.5 ml dexamethasone + 0.5 ml 1% lignocaine). The dose was repeated twice at weekly intervals. All patients were re assessed on Modified Tinnitus Handicap Inventory two weeks after third Intratympanic administration.

Timeline

Start
2021-03-01
Primary completion
2021-04
Completion
2021-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule 1.5 ml Other
Background Lidocaine Other / unclassified 0.5 ml Other

Indications