drugset / Trial / NCT04858360
Inhibition of Non-histaminergic Pruritus Applied Using 3 Different Pruritogens
NaSingle-groupOpen-labelBasic science
Summary
With this experiment, we want to use to investigate whether repeated application of EMLA cream as a tool to modulate non-histaminergic itching, which is produced using small needles from the plant mucuna pruriens (it is known that antihistamine does not attenuate this form of itch) and we want to compare the effect of short (1 hour) and prolonged (3 hours) application of EMLA. The sub-project takes place in 3 sessions over a period of 3 consecutive days (24 hours apart). All sessions will be identical.
Timeline
- Start
- 2021-11-15
- Primary completion
- 2022-08-01
- Completion
- 2022-10-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lidocaine | Other / unclassified | 2.5 % | Other |
| Subject | prilocaine | Small molecule | 2.5 % | Other |
Indications
No indication recorded.