drugset / Trial / NCT04880928
Comparison Mydriasis by Mydrane With Topical Drop Application
RandomizedCrossoverSingle-blindTreatment
Summary
The primary aim of the study is to compare the effectiveness of the intracameral application of Mydrane® (standardized combination of Tropicamide 0.02%, Phenylephrine 0.31% and Lidocaine 1%) with the preoperative topical application (Tropicamide 0.5% and Phenylephrine 10%). To evaluate the steadiness of the dilating effect on the pupil, the ratio of eyes without necessity for further pupil dilating procedures to perform the capsulorhexis is assessed.
Timeline
- Start
- 2020-08-12
- Primary completion
- 2021-09-23
- Completion
- 2021-09-23
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lidocaine | Other / unclassified | 10 mg/ml | Other |
| Comparator | Phenylephrine | Small molecule | 3.1 mg/ml | Other |
| Comparator | Phenylephrine | Small molecule | 10 % | Other |
| Comparator | tropicamide | Small molecule | 0.2 mg/ml | Other |
| Comparator | tropicamide | Small molecule | 0.5 % | Other |