drugset / Trial / NCT04934748
The GUARDIAN Trial - Vasopressor Sub-Study
Phase 4
Enrolling by invitation
6254 enrolled
The University of Texas Health Science Center, Houston
RandomizedFactorialDouble-blindPrevention
Summary
This is a sub-study of the overall GUARDIAN trial (NCT04884802) in which some GUARDIAN trial participants will be additionally randomized to norepinephrine or phenylephrine infusion to maintain the designated target intraoperative mean arterial pressure.
Timeline
- Start
- 2021-07-25
- Primary completion
- 2026-12-31
- Completion
- 2027-04-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Norepinephrine | Other / unclassified | — | Other |
| Comparator | Phenylephrine | Small molecule | — | Other |