drugset / Trial / NCT04965688

Biology Guided Therapy for Breast Cancer for ER Positive

NCT04965688

NaSingle-groupOpen-labelTreatment

Summary

There are several approved and guideline-recommended treatments for metastatic, estrogen receptor-positive breast cancer that has progressed on an aromatase inhibitor and a CDK4/6 inhibitor. Right now, doctors do not have a good way of choosing between these treatments. Scientists we work with have come up with ways to use the biology of the tumor to try to predict which treatment is best. This study is being done to test if those predictions are right and to learn more about these tumors to design better treatments in the future.

Timeline

Start
2021-08-08
Primary completion
2024-03-13
Completion
2024-03-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Alpelisib Small molecule
Subject Capecitabine Small molecule
Subject Everolimus Small molecule
Subject Exemestane Small molecule
Subject Fulvestrant Small molecule