drugset / Trial / NCT04983966

Comparison of Postoperative QoR-15 Scores Between Desflurane and Remimazolam in Lumbar Fusion Surgery

NCT04983966

Completed 76 enrolled Gangnam Severance Hospital
RandomizedParallel-groupTriple-blindOther

Summary

The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the lumbar fusion surgery. Total intravenous anesthesia (TIVA) have been known to help reducing risks of postoperative nausea/vomiting and malignant hyperthermia. However, it is still not enough to explain which is better between TIVA or inhalation anesthesia. In particular, there is no study to investigate overall postoperative functional recovery via QoR-15 in patients receiving TIVA with remimazolam. The hypothesis of our study is that total intravenous anesthesia based on remimazolam will demonstrate better quality of recovery compared with the anesthesia based on inhalation using desflurane.

Timeline

Start
2021-08-04
Primary completion
2024-02-14
Completion
2024-02-14

Drugs

EvaluationDrugModalityDoseRoute
Subject Desflurane Other / unclassified Inhaled
Comparator Remimazolam Small molecule 0.5 mg/kg Intravenous
Comparator Remimazolam Small molecule 1.5 mg/kg Intravenous

Indications

No indication recorded.